I'm thinking about using DMT or Mushrooms.

Bit of a claim that shrooms 'cure mental illness’.

There is some evidence it can help depression in some people.

It can also give you a nightmare trip, psychotic episodes, flashbacks, and fuck you up.

You really need to get proper advice before trying it.

If you do go ahead... Don't trip alone, have someone you really trust with you to see you through it... Do it in a safe space... Start with small amounts... Have a bucket ready for the vomiting.

Personally, I would humbly suggest you get your doctor to refer you to a course of CBT, and see if that helps your depression.