NFL 18 game schedule, 16 games max per player

So, If I understand correctly, Every team is going to have to bench every player two games a season. That includes quarterbacks. Who decides which games? Does it make any sense for Cleveland to bench Baker Mayfield for Game 1? Dallas will have to play two games each without Dak Prescott and Zeke Elliott? Buffalo is actually in a playoff hunt and has to bench Josh Allen for a key game? KC and the Chargers are tied going into the last week and the Chiefs have to bench key players while the Chargers opponents field a bunch of scrubs?

One last question, were they smoking PCP or dropping acid?