Actors who have played both iconic villains and heros

Some of these roles may not be "iconic", but they are surely well-known:

Marlon Brando - Terry Malone (On the Waterfront); Colonel Kurtz (Apocalypse Now)
Henry Fonda - Juror #8 (12 Angry Men); Frank (Once Upon a Time in the West)
Al Pacino - Michael Corleone (The Godfather trilogy); Frank Serpico (Serpico)
Gene Hackman - "Popeye" Doyle* (The French Connection); Lex Luthor (Superman film series)

* His character is more to be considered as an anti-hero.